We concluded an exciting year with our annual Christmas party - many thanks to all lab members for a great year 2024!
01 Dec 2024
Our project on investigating endolysosmal dysfunction in #iPSC-derived models of neurodegenerative diseases was selected for funding by the Alzheimer's Association. Many thanks for your support!
10 Nov 2024
Our project on programming microglia to target Alzheimer's disease was funded by Alzheimer Forschung Initiative (AFI)! Many thanks for your support!
Dominik and Judit joined the Leducq Meeting in Burlington, USA, hosted by Mark Nelson’s group, to present our work on the iPSC-derived BBB model.
10 Aug 2024
We celebrated Angelika's PhD at the GSN graduation day ceremony. Congrats again to a truly deserved PhD!
05 July 2024
We co-organized our institute's annual scientific retreat, with presentations and posters from lab and institute's members, and an exciting talk from our fantastic guest speaker Moritz Helmstaedter from MPI for Brain Research about connectomics!
07 June 2024
New paper with last author contribution from the lab in STM: ‘Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration’. Big congrats Matt and Marvin and many thanks to all involved!
Dominik presented Judit’s work on a fully human iPSC-derived model of the blood-brain-barrier at the EMBO BuildNetworks meeting in Barcelona.
02 May 2024
Dominik presented our work in an invited talk at Vall d’Hebron Institut de Recerca. Many thanks for the invitation!
02 April 2024
Angelika Dannert, GSN graduate student from the lab working on an iPSC model of Tauopathies, graduated with flying colors. Big congrats to Angelika (and thanks lab for the nice hat)!!
19 Mar 2024
Dominik presented a talk at the StemCellTuebingen meeting, and several lab members presented posters. Big congrats to PhD student Carolina Gonçalves for winning the best poster prize!
12 Mar 2024
New preprint in collaboration with CreminsLab on genome’s structure-function relationship in post-mitotic human neurons and a neurological disease context.
New preprint in collaboration with CreminsLab on genome’s structure-function relationship in post-mitotic human neurons and a neurological disease context.
Dominik chaired the session on Vascular Disease Mechanism and presented our work on generating a human iPSC-derived model of the BBB at the international ADPD meeting in Lisbon.
18 Jan 2024
Dominik explained our work on human iPSC models of brain diseases in the newest episode of the SyNergy_Cluster podcast (in German).
Our project 'Towards druggable targets in Alzheimer’s disease through characterization of PLCG2-related pathways in neurons and microglia (AD-PLCG2) was funded by JPND! We look forward to collaborating with the Lambert, Juhasz, Lichtenthaler and other labs!
Great to be back at the 21st Eibsee Meeting on Neudegeneration. Fantastic science - and big congrats to PhD student Merle Bublitz for winning the prize for the best flash talk!
7 Oct 2023
Big congrats to PhD student Angelika for winning the ‘Bioneer Best Speaker Award’ from the International Society of Molecular Neurodegeneration (ISMND)!
6 Oct 2023
We are very proud of Judit Gonzalez Gallego, who successfully defended her great PhD work co-supervised by Martin Dichgans and Dominik. Congratulations Judit and many thanks for your nice work! And thanks lab for the wonderful hat!
1 Oct 2023
We are delighted to receive a research grant from the German Ministry for Education and Research BMBF for a collaboration with ISAR Bioscience GmbH on our human iPSC-based brain tissue models for Alzheimer’s disease! Many thanks for the support. For further info, see here...
Dominik presented our work at the Endolysosomal x Neuroimmune Consortium Meeting in Gloucester, USA. And he also helped eating all the leftover lobster...
5 Sept 2023
Dominik was invited to present the Keynote lecture at the PORT for Health Neuroscience meeting in Wroclaw, Poland. Thanks for the invitation!
3 Aug 2023
We are delighted to receive a prestigious research grant from the Alzheimer’s Association for the E2A program for our project on investigating molecular disease mechanism in a human model of FTD-GRN. Many thanks! For further info, see here...
We are very proud of Sophie Robinson, who successfully defended her nice PhD work co-supervised by Christian Haass and Dominik. Congratulations Sophie and good luck with your new job in Boston! And thanks lab for the wonderful hat!
6 July 2023
We had again a great time at the ISD retreat and Carolina presented her project.
18 June 2023
Dominik presented Judit’s work in a talk at the CVB Neurovascular Meeting in Uppsala, Sweden.
Congratulations to Joey Kroeger, who successfully defended his PhD work! Thanks for your work and best of luck for your new job in Planegg! And thanks lab for the wonderful hat!
Judit and Dominik joined the first meeting of our new Leducq network in NYC to present and discuss our work and set up some nice collaborations.
17 Feb 2023
Congratulations to Liliana Pedro Dominguez, who successfully defended her PhD co-supervised by Mika Simons and Dominik! Thanks for your nice work and best of luck for your new job in Hamburg! And thanks lab for the wonderful hat!
01 Jan 2023
We are delighted to receive a prestigious research grant from Foundation Leducq for our collaborative project BRENDA - International Network of Excellence on Brain Endothelium - A Nexus for Cerebral Small Vessel Disease. For further info, see https://www.brenda-leducq.de
Judit presented her work at the EMBO Neurovascular interface meeting in Heidelberg in a talk.
15 Nov 2022
Several lab members joined the International Eibsee Conference to present our work and exchange ideas.
1 Nov 2022
Get-together to welcome the newest Baby-lab-member!
25 Oct 2022
Dominik presented our work at the International ISMND Conference in Athens, Greece and received an award for the best talk. Many thanks for selecting our work!
18 Oct 2022
We are very proud of Julien Klimmt, who defended his great PhD work successfully. Congratulations Julien and many thanks for your nice work! And thanks lab for the wonderful hat!
30 Sept 2022
The lab joined the Oktoberfest lecture with special guest Matt Blurton-Jones. Thanks, Matt, for coming and enjoying the “Wiesn” with us.
The lab was again very strong at b2run 2022, a running event of Munich companies and institutes.
11 July 2022
We hosted Martin Kampmann from UCSF for a research talk, discussions with lab members, and a “PI hike” around Zugspitze. Thanks, Martin, for visiting us!
7 July 2022
We had a nice and scientifically stimulating ISD retreat at Ammersee.
03 July 2022
Judit and Dominik joined a fantastic workshop “Mechanism of Cerebral Small Vessel Disease” in Crans-Montana, Switzerland, for extended discussions with leaders in the field.
27 June 2022
Several lab members attended the 2022 Stem Cell Workshop in Tübingen, Germany. Dominik presented a research talk and Julien and Angelika posters. Big congrats to Angelika for winning the best poster award!
5 April 2022
We are delighted to receive a research grant on our human iPSC-based model of Tauopathies from the Brightfocus Foundation! Many thanks for your support!
15 March 2022
Sophie and Julien presented posters at the international AD/PD meeting in Barcelona, and Dominik chaired a session and presented several cool lab projects in a talk.
We had a small socially distanced lab get together and got an exciting tour of the technical parts of our research building.
30 Oct 2021
Two posters from the lab at #NHAD21 in Leuven from @JulienKlimmt and @AngelikaDannert about our iPSC-derived models of Alzheimer’s and Tauopathies.
15 Oct 2021
Dominik presented our work on iPSC-derived human brain tissue models of neurodegenerative and neurovascular diseases at the German stem cell conference #GSCN21
We made a very nice (and long overdue…) lab trip by bike to Lake Starnberg with Pizza, beach volleyball and swimming - beautiful and warm day!
15 July 2021
We are really excited and happy that one the lab’s first PhD students successfully defended her thesis! Big congrats Isabel Weisheit and all the best for your future (and thanks lab for the fantastic hat…)!
10 July 2021
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We just posted a preprint on BioRxiv: Loss of TREM2 reduces hyperactivation of progranulin deficient microglia but not lysosomal pathology. Great collaboration with the labs of Christian Haass at DZNE and Kathryn Monroe at DENALI Inc.! Congrats Annika and Sophie!
Our newest Nature protocols paper was selected by Nature protocols editors to be presented as #Featured Protocol on the main page!
17 Feb 2021
Our newest paper was just published at Nature Protocols: Simple and reliable detection of CRISPR-induced on-target effects by qgPCR and SNP genotyping. See paper here, and Tweetorial summary here.
17 Dec 2020
We had a great virtual Christmas party with a cooking kit, dinner by zoom, and virtual games. Thanks lab for the nice evening!
11 Dec 2020
Dominik presented our recent work at the virtual Neuronus conference to a large (>100) audience of international young neuroscientists.
08 Dec 2020
We are very proud of Katja Salbaum, who won the award of the GBM (German Society for Biochemistry and Molecular Biology) for the best master thesis in Biomedical Neuroscience at TUM for her work on CRISPR base editing in iPSCs! Congratulations!
07 Dec 2020
Dominik gave the keynote lecture at the virtual 6th JNCL Young Investigator Symposium. Was a pleasure the learn more about NCL and related diseases and present our relevant work for this field.
01 Dec 2020
Dominik taught his first ‚socially distanced‘ lab course on molecular biology at TUM‘s Biomedical Neuroscience Master program. This was quite different to previous years, but worked quite well overall and made the students happy, as they could meet in person for the first time since they started their MSc studies.
23 Sep 2020
Isabel was selected for a talk at the German Stem Cell Network (GSCN) Conference and presented this virtually to the audience, with lots of good questions afterwards. Read more...
10 Jun 2020
We use the nice weather and end of the lockdown to make a ‚socially distanced‘ lab hike to the mountains around Lenggries near Munich. Really nice warm day with lots of wildflowers!
01 Jun 2020
We are delighted to be selected for an iAward of the Sanofi Innovation Awards Europe Program 2020 for our work on iPSC models of Neurodegenerative diseases. Many thanks to Sanofi for the support, we look forward to working with you!
26 May 2020
Taming widespread collateral damage of CRISPR editing
